What about eye health and Folates?
Is the elimination of deficiencies a target?

The energy consumption of the eye is higher than of any other organ in the body. It is therefore reasonable that a systemic or local problem of the supply system can cause a deficiency of oxygen in the eye but also create a shortage of Folates and other micronutrients.

Aprofol recently sponsored a pilot study with the aim to investigate the effect of Ocufolin^® forte on the Homocysteine-level (Hcy) and on ocular blood flow parameters. 24 diabetic patients with a moderately elevated Hcy-value have taken one capsule per day over 3 months.

After 12 weeks the Hcy-level was on average 32 % lower, the average of all participants was in the normal range. Comparable studies achieved a decrease of around 25 %. In addition to the surprisingly efficient reduction of the Hcy-level, a strong trend for an increased retinal blood flow and a statistically significant reduction of the intraocular pressure was observed.

The decrease of the indicator of several possible deficiencies (Hcy) was expected. Beyond this decrease and for the first time, an improvement of important blood flow parameters was found.

The results of this pilot study to assess the effect of a three-month vitamin supplementation containing L-methylfolate on systemic homocysteine plasma concentrations and retinal blood flow in patients with diabetes are published in the Journal Molecular Vision (https://www.ncbi.nlm.nih.gov/pubmed/32355442). The goal of Aprofol is to confirm these data in a placebo-controlled study.

Learn more about Eye Health and Folate as well as about Ocufolin^®.